Newton:Spectral Deconvolution of Multidimensional NMR Data

Newton is a multi-platform, Java-based framework for spectral analysis of multidimensional NMR data. Newton implements fast maximum likelihood reconstruction (FMLR), a form of spectral deconvolution that constructs the simplest time-domain model whose fourier processed spectrum most closely matches the spectrum of the identically processed FID.

FMLR as implemented by Newton is currently being applied to numerous areas of NMR spectral analysis:

Applications of Fast Maximum Likelihood Reconstruction (FMLR)
Area Application Goal
General NMR Spectral analysis Quantitative analysis of n-dimensional NMR spectra data sets including related data sets by spectral deconvolution.
Metabolomics Complex mixture analysis Identification and quantification of metabolites present in biological fluids and extracts from 1D and 2D NMR spectra.
Biofuels Research Plant cell wall profiling Fingerprinting of polysaccharide and lignin components in unfractionated cell wall material, including derivation of lignin S/G/H lignin ratios

Installation and Launch